Brefeldin A (ab120299)
货 号：ab120299
产品规格：5mg
原 产 地：abcam
参考价格：899 （参考价格，以实际价格为准）
优惠价格：
Brefeldin A (ab120299) ab120299 abcam
Product nameBrefeldin A
Description
Inhibitor of ADP-ribosylation factor
Alternative names
Ascotoxin
BFA
Cyanein
Decumbin
Biological descriptionReversible inhibitor of protein translocation from the endoplasmic reticulum to the Golgi apparatus. Inhibits binding of the cytosolic coat protein, β-COP and ADP-ribosylation factor (ARF) to Golgi membranes and inhibits GDP-GTP exchange.
Purity> 99%
- Molecular formulaC16H24O4
- CAS Number20350-15-6
- PubChem identifier5287620
- Solubility overviewSoluble in DMSO to 50 mM
This product has been referenced in:
- Lippincott-Schwartz J et al. Brefeldin A’s effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell 67:601-16 (1991). Read more (PubMed: 1682055) »
- Donaldson JG et al. Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus. J Cell Biol 112:579-88 (1991). Read more (PubMed: 1993732) »
- Pelham HR Multiple targets for brefeldin A. Cell 67:449-51 (1991). Read more (PubMed: 1934055) »
产品详细信息
Brefeldin A (ab120299) ab120299 abcam
Product nameBrefeldin A
Description
Inhibitor of ADP-ribosylation factor
Alternative names
Ascotoxin
BFA
Cyanein
Decumbin
Biological descriptionReversible inhibitor of protein translocation from the endoplasmic reticulum to the Golgi apparatus. Inhibits binding of the cytosolic coat protein, β-COP and ADP-ribosylation factor (ARF) to Golgi membranes and inhibits GDP-GTP exchange.
Purity> 99%
- Molecular formulaC16H24O4
- CAS Number20350-15-6
- PubChem identifier5287620
- Solubility overviewSoluble in DMSO to 50 mM
This product has been referenced in:
- Lippincott-Schwartz J et al. Brefeldin A’s effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell 67:601-16 (1991). Read more (PubMed: 1682055) »
- Donaldson JG et al. Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus. J Cell Biol 112:579-88 (1991). Read more (PubMed: 1993732) »
- Pelham HR Multiple targets for brefeldin A. Cell 67:449-51 (1991). Read more (PubMed: 1934055) »