Anti-Human CD22 FITC
货 号：11-0229-41
产品规格：25tests
原 产 地：USA
参考价格：1188 （参考价格，以实际价格为准）
优惠价格：
Anti-Human CD22 FITC
11-0229-41
25tests
USA
The eBio4KB128 monoclonal antibody recognizes human CD22 (Siglec-2),which is a member
of the siglec subgroup of the Ig superfamily. CD22 is a type Itransmembrane glycoprotein
composed of two polypeptide chains, CD22α and CD22β, of 130 and 140 kDa respectively,
produced by alternative splicing of the CD22 gene. CD22 is expressed athigh levels on
mature B cells and B cell lymphomas. The extracellular portion of CD22contains seven
Ig-like domains, some of which are capable of binding ligands withsialic acid moieties
expressed on epithelial, endothelial, B and T cells. The intracellularportion of CD22
contains 6 tyrosine residues contained within immunotyrosine-basedinhibitory motifs (ITIM) and
immunotyrosine-based activation-like motifs, which are phosphorylatedupon B-cell receptor
engagement, which enables CD22 to participate in the positive andnegative regulation of
B-cell receptor signaling.
产品详细信息
Anti-Human CD22 FITC
11-0229-41
25tests
USA
The eBio4KB128 monoclonal antibody recognizes human CD22 (Siglec-2),which is a member
of the siglec subgroup of the Ig superfamily. CD22 is a type Itransmembrane glycoprotein
composed of two polypeptide chains, CD22α and CD22β, of 130 and 140 kDa respectively,
produced by alternative splicing of the CD22 gene. CD22 is expressed athigh levels on
mature B cells and B cell lymphomas. The extracellular portion of CD22contains seven
Ig-like domains, some of which are capable of binding ligands withsialic acid moieties
expressed on epithelial, endothelial, B and T cells. The intracellularportion of CD22
contains 6 tyrosine residues contained within immunotyrosine-basedinhibitory motifs (ITIM) and
immunotyrosine-based activation-like motifs, which are phosphorylatedupon B-cell receptor
engagement, which enables CD22 to participate in the positive andnegative regulation of
B-cell receptor signaling.