Brefeldin A (ab120299) 货号:ab120299

Brefeldin A (ab120299) 货号:ab120299

Brefeldin A (ab120299)

货  号:ab120299

产品规格:5mg

原  产  地:abcam

参考价格:899 (参考价格,以实际价格为准)

优惠价格:

产品详细信息

Brefeldin A (ab120299)  ab120299  abcam

    Product nameBrefeldin A
    Description
    Inhibitor of ADP-ribosylation factor
    Alternative names
        Ascotoxin
        BFA
        Cyanein
        Decumbin
    Biological descriptionReversible inhibitor of protein translocation from the endoplasmic reticulum to the Golgi apparatus. Inhibits binding of the cytosolic coat protein, β-COP and ADP-ribosylation factor (ARF) to Golgi membranes and inhibits GDP-GTP exchange.
    Purity> 99%

  • Molecular formulaC16H24O4
  • CAS Number20350-15-6
  • PubChem identifier5287620
  • Solubility overviewSoluble in DMSO to 50 mM

This product has been referenced in:
  • Lippincott-Schwartz J  et al. Brefeldin A’s effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell 67:601-16 (1991). Read more (PubMed: 1682055) »
  • Donaldson JG  et al. Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus. J Cell Biol 112:579-88 (1991). Read more (PubMed: 1993732) »
  • Pelham HR Multiple targets for brefeldin A. Cell 67:449-51 (1991). Read more (PubMed: 1934055) »

产品详细信息

Brefeldin A (ab120299)  ab120299  abcam

    Product nameBrefeldin A
    Description
    Inhibitor of ADP-ribosylation factor
    Alternative names
        Ascotoxin
        BFA
        Cyanein
        Decumbin
    Biological descriptionReversible inhibitor of protein translocation from the endoplasmic reticulum to the Golgi apparatus. Inhibits binding of the cytosolic coat protein, β-COP and ADP-ribosylation factor (ARF) to Golgi membranes and inhibits GDP-GTP exchange.
    Purity> 99%

  • Molecular formulaC16H24O4
  • CAS Number20350-15-6
  • PubChem identifier5287620
  • Solubility overviewSoluble in DMSO to 50 mM

This product has been referenced in:
  • Lippincott-Schwartz J  et al. Brefeldin A’s effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell 67:601-16 (1991). Read more (PubMed: 1682055) »
  • Donaldson JG  et al. Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus. J Cell Biol 112:579-88 (1991). Read more (PubMed: 1993732) »
  • Pelham HR Multiple targets for brefeldin A. Cell 67:449-51 (1991). Read more (PubMed: 1934055) »

Brefeldin A 货号:1560-5

Brefeldin A 货号:1560-5

Brefeldin A

货  号:1560-5

产品规格:5mg

原  产  地:BioVision

参考价格:1360 (参考价格,以实际价格为准)

优惠价格:

产品详细信息

Brefeldin A

Ascotoxin, BFA, Cyanein, Decumbin, γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone
背景资料     

提供的Brefeldin A产品属于生化试剂。
产品描述     Brefeldin A has been shown to induce apoptosis in human tumor cells through caspase activation. It has also been shown to block translocation of proteins from the endoplasmic reticulum to the Golgi apparatus.

产品详细信息

Brefeldin A

Ascotoxin, BFA, Cyanein, Decumbin, γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone
背景资料     

提供的Brefeldin A产品属于生化试剂。
产品描述     Brefeldin A has been shown to induce apoptosis in human tumor cells through caspase activation. It has also been shown to block translocation of proteins from the endoplasmic reticulum to the Golgi apparatus.

细胞因子刺激剂Brefeldin A Solution (1,000X) 货号:1 ml

细胞因子刺激剂Brefeldin A Solution (1,000X) 货号:1 ml

细胞因子刺激剂Brefeldin A Solution (1,000X)

货  号:1 ml

产品规格:420601

原  产  地:biolegend

参考价格:658 (参考价格,以实际价格为准)

优惠价格:

产品详细信息

细胞因子刺激剂Brefeldin A Solution (1,000X)  420601  biolegend  1 ml

Formulation:     Brefeldin A Solution is supplied as a 1000X in DMSO, which should be diluted to 1X in cell culture medium.
Concentration:     5.0 mg/ml
Storage & Handling:     Store the Brefeldin A Solution (1,000X) between 2°C and 8°C. Note: DMSO freezes at this temperature.
Application
References:

1. O’Sullivan BJ, et al. 2006. J. Immunol. 176:7278.
2. Fuse S, et al. 2007. J. Immunol. 178:5227.
3. Kang YJ, et al. 2007. Nature Immunol. 8:601.
4. Redfern CH,et al.2006.J. Clin Oncol.19:3107.PubMed
5. Smithey MJ, et al. 2008. J. Immunol. 180:3406. PubMed
6. Elzey BD, et al. 2008. Blood 111:38684. PubMed
7. Nguyen KD, et al. 2008. J. Immunol. 181:5386. PubMed
8. Miner MD, et al. 2008. Microb Pathog. 45:273. PubMed
9. Goodridge HS, et al. 2009. J. Immunol. 182:1146. PubMed
10. Markey KA, et al. 2009. Blood 113:5644. PubMed
11. Wilcox RA, et al. 2009. Blood PubMed
12. Zenaro E, et al. 2009. J. Leukoc Bio. PubMed

细胞因子刺激剂
BioLegend 细胞激活混合物运输条件经过严格的稳定性验证,确保运输过程不会对产品质量产生任何影响!
货号        产品名称    规格                                          促销价
420601 Brefeldin A Solution (1,000X) 1 ml          658
420701 Monensin Solution (1,000X) 1 ml            493
423301/423302 Cell Activation Cocktail (without Brefeldin A) 100 ul/400 ul 888/2463
423303/423304 Cell Activation Cocktail (with Brefeldin A) 100 ul/400 ul 1218/2853

产品详细信息

细胞因子刺激剂Brefeldin A Solution (1,000X)  420601  biolegend  1 ml

Formulation:     Brefeldin A Solution is supplied as a 1000X in DMSO, which should be diluted to 1X in cell culture medium.
Concentration:     5.0 mg/ml
Storage & Handling:     Store the Brefeldin A Solution (1,000X) between 2°C and 8°C. Note: DMSO freezes at this temperature.
Application
References:

1. O’Sullivan BJ, et al. 2006. J. Immunol. 176:7278.
2. Fuse S, et al. 2007. J. Immunol. 178:5227.
3. Kang YJ, et al. 2007. Nature Immunol. 8:601.
4. Redfern CH,et al.2006.J. Clin Oncol.19:3107.PubMed
5. Smithey MJ, et al. 2008. J. Immunol. 180:3406. PubMed
6. Elzey BD, et al. 2008. Blood 111:38684. PubMed
7. Nguyen KD, et al. 2008. J. Immunol. 181:5386. PubMed
8. Miner MD, et al. 2008. Microb Pathog. 45:273. PubMed
9. Goodridge HS, et al. 2009. J. Immunol. 182:1146. PubMed
10. Markey KA, et al. 2009. Blood 113:5644. PubMed
11. Wilcox RA, et al. 2009. Blood PubMed
12. Zenaro E, et al. 2009. J. Leukoc Bio. PubMed

细胞因子刺激剂
BioLegend 细胞激活混合物运输条件经过严格的稳定性验证,确保运输过程不会对产品质量产生任何影响!
货号        产品名称    规格                                          促销价
420601 Brefeldin A Solution (1,000X) 1 ml          658
420701 Monensin Solution (1,000X) 1 ml            493
423301/423302 Cell Activation Cocktail (without Brefeldin A) 100 ul/400 ul 888/2463
423303/423304 Cell Activation Cocktail (with Brefeldin A) 100 ul/400 ul 1218/2853