SIGLEC15 Antibody (C-term) 货号:AP11503b

SIGLEC15 Antibody (C-term) 货号:AP11503b

SIGLEC15 Antibody (C-term)

货  号:AP11503b

产品规格:100UL

原  产  地:USA

参考价格:1100 (参考价格,以实际价格为准)

优惠价格:

产品详细信息

SIGLEC15 Antibody (C-term) – Product info

Application WB, IHCPrimary AccessionQ6ZMC9Other AccessionNP_998767.1ReactivityHumanIsotypeRabbit 

IgCalculated MW35653 DaSIGLEC15 Antibody (C-term) – Additional infoGene ID284266Other Names
SIGLEC15; CD33L3; Sialic acid-binding Ig-like lectin 15; CD33 antigen-like 3Target/Specificity
This SIGLEC15 antibody is generated from rabbits immunized with a KLH conjugated synthetic
 peptide between 274-302 amino acids from the C-terminal region of human SIGLEC15.Dilution
WB~~1:1000
IHC~~1:10~50

产品详细信息

SIGLEC15 Antibody (C-term) – Product info

Application WB, IHCPrimary AccessionQ6ZMC9Other AccessionNP_998767.1ReactivityHumanIsotypeRabbit 

IgCalculated MW35653 DaSIGLEC15 Antibody (C-term) – Additional infoGene ID284266Other Names
SIGLEC15; CD33L3; Sialic acid-binding Ig-like lectin 15; CD33 antigen-like 3Target/Specificity
This SIGLEC15 antibody is generated from rabbits immunized with a KLH conjugated synthetic
 peptide between 274-302 amino acids from the C-terminal region of human SIGLEC15.Dilution
WB~~1:1000
IHC~~1:10~50

SIGLEC15 Antibody (C-term) 货号:AP11503b

SIGLEC15 Antibody (C-term) 货号:AP11503b

SIGLEC15 Antibody (C-term)

货  号:AP11503b

产品规格:100UL

原  产  地:USA

参考价格:1100 (参考价格,以实际价格为准)

优惠价格:

产品详细信息

SIGLEC15 Antibody (C-term) – Product info

Application WB, IHCPrimary AccessionQ6ZMC9Other AccessionNP_998767.1ReactivityHumanIsotypeRabbit 

IgCalculated MW35653 DaSIGLEC15 Antibody (C-term) – Additional infoGene ID284266Other Names
SIGLEC15; CD33L3; Sialic acid-binding Ig-like lectin 15; CD33 antigen-like 3Target/Specificity
This SIGLEC15 antibody is generated from rabbits immunized with a KLH conjugated synthetic
 peptide between 274-302 amino acids from the C-terminal region of human SIGLEC15.Dilution
WB~~1:1000
IHC~~1:10~50

产品详细信息

SIGLEC15 Antibody (C-term) – Product info

Application WB, IHCPrimary AccessionQ6ZMC9Other AccessionNP_998767.1ReactivityHumanIsotypeRabbit 

IgCalculated MW35653 DaSIGLEC15 Antibody (C-term) – Additional infoGene ID284266Other Names
SIGLEC15; CD33L3; Sialic acid-binding Ig-like lectin 15; CD33 antigen-like 3Target/Specificity
This SIGLEC15 antibody is generated from rabbits immunized with a KLH conjugated synthetic
 peptide between 274-302 amino acids from the C-terminal region of human SIGLEC15.Dilution
WB~~1:1000
IHC~~1:10~50

Anti-Mouse Siglec H FITC 货号:11-0333-82

Anti-Mouse Siglec H FITC 货号:11-0333-82

Anti-Mouse Siglec H FITC

货  号:11-0333-82

产品规格:100ug

原  产  地:USA

参考价格:1908 (参考价格,以实际价格为准)

优惠价格:

产品详细信息

Anti-Mouse Siglec H FITC

11-0333-82
100ug
USA

The monoclonal antibody eBio440c recognizes Siglec-H, a proteinexclusively found on

pDC (plasmacytoid dendritic cells) or type I IFN-producing cells (IPC)in the naïve mouse.
Mouse IPC are typically PDCA+, CD11c+, CD11b-, B220+, and Ly-6C+, andare quick to respond
to viruses. Siglec-H is a transmembrane protein of the Ig superfamilythat like CD33 have
been shown to bind sialic acid but lacks the characteristic cytoplasmic ITIM
domain (immunoreceptor tyrosine based inhibitory motif). To overcomethe lack of a
cytoplasmic domain, Siglec-H associates with DAP12 thereby allowing forsignal transduction.

The eBio440c antibody has been shown to inhibit pDC function (inhbitsIFNalpha secretion
in response to CpG).

It has been observed that some mouse strains (such as SJL) have higherpercentages of pDCs
compared to C57BL/6.

产品详细信息

Anti-Mouse Siglec H FITC

11-0333-82
100ug
USA

The monoclonal antibody eBio440c recognizes Siglec-H, a proteinexclusively found on

pDC (plasmacytoid dendritic cells) or type I IFN-producing cells (IPC)in the naïve mouse.
Mouse IPC are typically PDCA+, CD11c+, CD11b-, B220+, and Ly-6C+, andare quick to respond
to viruses. Siglec-H is a transmembrane protein of the Ig superfamilythat like CD33 have
been shown to bind sialic acid but lacks the characteristic cytoplasmic ITIM
domain (immunoreceptor tyrosine based inhibitory motif). To overcomethe lack of a
cytoplasmic domain, Siglec-H associates with DAP12 thereby allowing forsignal transduction.

The eBio440c antibody has been shown to inhibit pDC function (inhbitsIFNalpha secretion
in response to CpG).

It has been observed that some mouse strains (such as SJL) have higherpercentages of pDCs
compared to C57BL/6.