Substance P ELISA kitP物质 货号:ADI-900-018

Substance P ELISA kitP物质 货号:ADI-900-018

Substance P ELISA kitP物质

货  号:ADI-900-018

产品规格:96T

原  产  地:ENZO

参考价格:4990 (参考价格,以实际价格为准)

优惠价格:3996

产品详细信息

Substance P ELISA kitP物质 ADI-900-018  ENZO

Product Specification
Sensitivity:    8.04 pg/ml (range 9.76 – 10,000 pg/ml)
 
Assay Time:    3 hours
 
Application:    For the quantitative determination of Substance P in culture supernatants, plasma, serum, saliva, and urine from any species. Cited sample type includes tissue (ref. 1).
 
Use/Stability:    Store all components at 4°, except standard and conjugate at -20°.
 
Kit/Set Contains:    GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution
 
Miscellaneous/General:    Substance P is an undecapeptide hormone (RPKPQQFFGLM) that mediates a number of biological activities including nausea, anxiety, pain, and vasodilation. It is a member of the tachykinin family of neuropeptides, and is widely distributed in the peripheral and central nervous systems of vertebrates.

Product Literature References

Effect of anti-NGF antibodies in a rat tibia fracture model of complex regional pain syndrome type I : I. Sabsovich, et al. ; Pain 138, 47 (2008), (ref. 1), Abstract;
Endogenous ATP potentiates only vasopressin secretion from neurohypophysial terminals: J. Lemos, et al. ; J. Cell. Physiol. 217, 155 (2008), Application(s): EIA using rat culture supernatants, Abstract;
Tachykinin neurokinin 3 receptor signaling in cholecystokinin-elicited release of oxytocin and vasopressin: F. Flynn, et al. ; Am. J. Physiol. Regul. Integr. Comp. Physiol. 294, R1760 (2008), Application(s): EIA using rat plasma, Abstract;
Loss of Vav2 proto-oncogene causes tachycardia and cardiovascular disease in mice: X. Bustelo, et al. ; Mol. Biol. Cell 18, 943 (2007), Application(s): EIA using mouse plasma, Abstract;
Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge: G.E. Haley, et al. ; Am. J. Physiol. Regul. Integr. Comp. Physiol. 293, R931 (2007), Application(s): EIA using rat plasma (ref. 2), Abstract;
Urea transporter UT-A1 and aquaporin-2 proteins decrease in response to angiotensin II or norepinephrine-induced acute hypertension: J.D. Klein, et al. ; Ren. Physiol. 291, F952 (2006), Application(s): EIA using rat plasma, Abstract;

产品详细信息

Substance P ELISA kitP物质 ADI-900-018  ENZO

Product Specification
Sensitivity:    8.04 pg/ml (range 9.76 – 10,000 pg/ml)
 
Assay Time:    3 hours
 
Application:    For the quantitative determination of Substance P in culture supernatants, plasma, serum, saliva, and urine from any species. Cited sample type includes tissue (ref. 1).
 
Use/Stability:    Store all components at 4°, except standard and conjugate at -20°.
 
Kit/Set Contains:    GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution
 
Miscellaneous/General:    Substance P is an undecapeptide hormone (RPKPQQFFGLM) that mediates a number of biological activities including nausea, anxiety, pain, and vasodilation. It is a member of the tachykinin family of neuropeptides, and is widely distributed in the peripheral and central nervous systems of vertebrates.

Product Literature References

Effect of anti-NGF antibodies in a rat tibia fracture model of complex regional pain syndrome type I : I. Sabsovich, et al. ; Pain 138, 47 (2008), (ref. 1), Abstract;
Endogenous ATP potentiates only vasopressin secretion from neurohypophysial terminals: J. Lemos, et al. ; J. Cell. Physiol. 217, 155 (2008), Application(s): EIA using rat culture supernatants, Abstract;
Tachykinin neurokinin 3 receptor signaling in cholecystokinin-elicited release of oxytocin and vasopressin: F. Flynn, et al. ; Am. J. Physiol. Regul. Integr. Comp. Physiol. 294, R1760 (2008), Application(s): EIA using rat plasma, Abstract;
Loss of Vav2 proto-oncogene causes tachycardia and cardiovascular disease in mice: X. Bustelo, et al. ; Mol. Biol. Cell 18, 943 (2007), Application(s): EIA using mouse plasma, Abstract;
Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge: G.E. Haley, et al. ; Am. J. Physiol. Regul. Integr. Comp. Physiol. 293, R931 (2007), Application(s): EIA using rat plasma (ref. 2), Abstract;
Urea transporter UT-A1 and aquaporin-2 proteins decrease in response to angiotensin II or norepinephrine-induced acute hypertension: J.D. Klein, et al. ; Ren. Physiol. 291, F952 (2006), Application(s): EIA using rat plasma, Abstract;

Anti-Substance P Receptor Antibody, pain 货号:AB5060

Anti-Substance P Receptor Antibody, pain 货号:AB5060

Anti-Substance P Receptor Antibody, pain

货  号:AB5060

产品规格:50ul

原  产  地:Chemicon

参考价格:4107 (参考价格,以实际价格为准)

优惠价格:3171

产品详细信息

Anti-Substance P Receptor Antibody, pain AB5060

Species Reactivity    Key Applications    Host    Format    Antibody Type
R, Gp, M    WB, IF, IHC    Rb    Serum    Polyclonal Antibody
Catalogue Number     AB5060
Brand Family     Chemicon®
Synonyms     NK-1 Receptor
Trade Name     

    Chemicon

Description     Anti-Substance P Receptor Antibody, pain
Background Information     Substance P is a tachykinin family neuropeptide that functions as a neurotransmitter and neuromodulator. In the CNS, Substance P is involved in the regulation of mood, anxiety, sleep, saiety, reinforcement, respiratory rhythm and pain processing. In nociception, the neuropeptide is released at local spinal cord synapses. Recent research now shows substance P is potentially involved in endothelial cell differentiation as well as diverse roles in neuroinflammatory response. The endogenous receptor for Substance P is neurokinin 1 receptor (NK1 receptor), which belongs to the tachykinin receptor sub-family of GPCRs.
Product Information
Format     Serum
Specificity     Specific for the Substance P Receptor (NK-1).
Control     

    Spinal Cord, brain membrane lysate

Presentation     Rabbit polyclonal serum in buffer containing liquid with no preservatives.
Applications
Application     Anti-Substance P Receptor Antibody, pain detects level of Substance P Receptor & has been published & validated for use in IF, IH & WB.
Key Applications     

    Western Blotting
    Immunofluorescence
    Immunohistochemistry

Application Notes     Immunohistochemistry:
A previous lot was used at 1:100-1:1,000 dilution.

Western Blot Analysis:
A previous lot was used at 1:500 dilution.

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen species     Synthetic peptide that corresponds to a 23 amino acid sequence (385-407) of the COOH terminus of the rat Substance P Receptor (NK-1).
Epitope     C terminus
Concentration     Please refer to the Certificate of Analysis for the lot-specific concentration.
Host     Rabbit
Specificity     Specific for the Substance P Receptor (NK-1).
Species Reactivity     Rat Guinea Pig Mouse
Species Reactivity Note     Rat, mouse and guinea pig.
Antibody Type     Polyclonal Antibody
Entrez Gene Number     

    NM_003182.1

Entrez Gene Summary     This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene.

产品详细信息

Anti-Substance P Receptor Antibody, pain AB5060

Species Reactivity    Key Applications    Host    Format    Antibody Type
R, Gp, M    WB, IF, IHC    Rb    Serum    Polyclonal Antibody
Catalogue Number     AB5060
Brand Family     Chemicon®
Synonyms     NK-1 Receptor
Trade Name     

    Chemicon

Description     Anti-Substance P Receptor Antibody, pain
Background Information     Substance P is a tachykinin family neuropeptide that functions as a neurotransmitter and neuromodulator. In the CNS, Substance P is involved in the regulation of mood, anxiety, sleep, saiety, reinforcement, respiratory rhythm and pain processing. In nociception, the neuropeptide is released at local spinal cord synapses. Recent research now shows substance P is potentially involved in endothelial cell differentiation as well as diverse roles in neuroinflammatory response. The endogenous receptor for Substance P is neurokinin 1 receptor (NK1 receptor), which belongs to the tachykinin receptor sub-family of GPCRs.
Product Information
Format     Serum
Specificity     Specific for the Substance P Receptor (NK-1).
Control     

    Spinal Cord, brain membrane lysate

Presentation     Rabbit polyclonal serum in buffer containing liquid with no preservatives.
Applications
Application     Anti-Substance P Receptor Antibody, pain detects level of Substance P Receptor & has been published & validated for use in IF, IH & WB.
Key Applications     

    Western Blotting
    Immunofluorescence
    Immunohistochemistry

Application Notes     Immunohistochemistry:
A previous lot was used at 1:100-1:1,000 dilution.

Western Blot Analysis:
A previous lot was used at 1:500 dilution.

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen species     Synthetic peptide that corresponds to a 23 amino acid sequence (385-407) of the COOH terminus of the rat Substance P Receptor (NK-1).
Epitope     C terminus
Concentration     Please refer to the Certificate of Analysis for the lot-specific concentration.
Host     Rabbit
Specificity     Specific for the Substance P Receptor (NK-1).
Species Reactivity     Rat Guinea Pig Mouse
Species Reactivity Note     Rat, mouse and guinea pig.
Antibody Type     Polyclonal Antibody
Entrez Gene Number     

    NM_003182.1

Entrez Gene Summary     This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene.