C-6 NBD-二氢神经酰胺

C-6 NBD神经酰胺是短链膜可渗透神经酰胺的生物活性荧光类似物。它在抑制病毒糖蛋白通过高尔基体转运方面与C-6神经酰胺一样有效。1C-6 NBD神经酰胺已被用作UDP-葡萄糖：神经酰胺葡糖基转移酶2活性的荧光底物，并证明了葡萄糖脑苷脂的转运3 C-6 NBD-二氢-神经酰胺在结构上与C-6 NBD神经酰胺没有区别，只是它在鞘氨醇主链的C-4 / C-5位置含有一个饱和键。

C-6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C-6 ceramide in the inhibition of viral glycoprotein transport through the Golgi.1 C-6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase2 and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane.3 C-6 NBD-dihydro-Ceramide is structurally indistinguishable to C-6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone.