6-脱氧-D-葡萄糖
基本信息
产品名称 | 6-脱氧-D-葡萄糖 |
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英文名称 | 6-Deoxy-D-glucose |
规格或纯度 | ≥97% |
运输条件 | 超低温冰袋运输 |
一般描述
6-脱氧-D-葡萄糖是D-葡萄糖的结构同型物,由于在碳6上没有羟基,因此不能被己糖激酶或葡萄糖激酶磷酸化。 -D-葡萄糖可以通过促进扩散而运入和运出细胞。缺少其6-羟基基团可使6-脱氧-D-葡萄糖转运到细胞中并以未改变的状态完全恢复。众所周知,葡萄糖是一种重要的单糖,其充当细胞的能量来源。一些人认为,与其他单糖相比,葡萄糖的多功能性是由于葡萄糖更喜欢其环状形式,从而降低了糖基化这一事实。
6-Deoxy-D-glucose is a structural homomorph of D-glucose, which cannot be phosphorylated by hexokinases or glucokinases, as a result of its lack of a hydroxyl group at carbon 6. Studies on|Saccharomyces cerevisiae|show that 6-Deoxy-D-glucose can be transported in and out of the cell using facilitated diffusion. The lack of its 6-hydroxyl group allows 6-Deoxy-D-glucose to be transported into cells and fully recovered in an unchanged state. It is known that glucose is an important monosaccharide which functions as an energy source for cells. Some believe that the versatility of glucose compared to other monosaccharides is due to the fact that glucose prefers its cyclic form, which reduces glycation.
相关属性
CAS编号 | 7658-08-4 |
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比旋光度 | α20/D 30°±2°, c = 1.8-2.2 in water |
折光率 | n20D1.59 (Predicted) |
熔点 | 142-144° C |
沸点 | 323.91° C at 760 mmHg (Predicted) |
溶解性 | Soluble in water (~50 mg/ml). |
储存温度 | -20°C储存 |
密度 | 1.56 g/cm3(Predicted) |
分子量 | 164.16 |
分子式 | C₆H₁₂O₅ |
EC号 | 231-622-2 |
品牌 | Jinpan |
Smiles | C[C@@H]1[C@H]([C@@H]([C@H](C(O1)O)O)O)O |
PubChem CID | 439746 |