α-Gal 2-AA 聚糖
|产品名称||α-Gal 2-AA 聚糖|
|英文名称||Alpha Gal 2-AA Glycan|
Galactose-alpha-1,3-galactose, commonly known as alpha gal, is a carbohydrate found in mammalian meat products. Approximately 1% of immunoglobulins in humans are specific to alpha-gal, and these antibodies (anti- Gal) cause an allergic reaction. Due to its potential immunogenicity, it is important therefore to screen biopharmaceuticals for alpha-gal. Some drug developers are also investigating the use of anti-Gal for tumour therapies.
Dry. Dried by centrifugal evaporation from an aqueous solution.
Typically, 100 fmol to 10 pmol of the Alpha Gal 2-AA glycan can be detected, dependent on the sensitivity of the fluorometer, HPLC or mass spectrometer.
Fluorescence detection: 360 nm excitation wavelength, 420 nm emission wavelength.