Alpha Gal Glycan
|产品名称||Alpha Gal Glycan|
|英文名称||Alpha Gal Glycan|
The Alpha Gal glycan is a linear tetrasaccharide with sequence linkages Gal-alpha(1-3)-Gal-beta(1-4)-Gal-alpha(1-3)-Gal. This standard was developed as a positive control when using alpha galactosidase for biopharmaceutical glycoprofiling assays.
2-AB and a 2-AA Alpha Gal standard is also available.
Galactose-alpha-1,3-galactose, commonly known as alpha gal, is a carbohydrate found in mammalian meat products. Approximately 1% of immunoglobulins in humans are specific to alpha-gal, and these antibodies (anti- Gal) cause an allergic reaction. Due to its potential immunogenicity, it is important therefore to screen biopharmaceuticals for alpha-gal. Some drug developers are also investigating the use of anti-Gal for tumour therapies.
Form: Dry. Dried by centrifugal evaporation from an aqueous solution.
Amount of Sample: 33 µgs
Structural Integrity: Determined by MALDI mass spectrometry and HPLC.