α-Gal 2-AB 聚糖

产品介绍：

半乳糖-α-1，3-半乳糖，俗称α-半乳糖，是一种存在于哺乳动物肉制品中的碳水化合物。人类中大约1%的免疫球蛋白对α-半乳糖具有特异性，这些抗体（抗半乳糖）会引起过敏反应。由于其潜在的免疫原性，因此筛选生物药物的α-半乳糖非常重要。一些药物开发商也在研究抗Gal在肿瘤治疗中的应用。
形式：通过离心蒸发从水溶液中干燥。
样品数量：通常，根据荧光计、HPLC 或质谱仪的灵敏度，可以检测 100 fmol 至 10 pmol的 Alpha Gal 2-AB 聚糖。
检波荧光检测：320nm激发波长，420nm发射波长。

Product description：

Galactose-alpha-1,3-galactose, commonly known as alpha gal, is a carbohydrate found in mammalian meat products. Approximately 1% of immunoglobulins in humans are specific to alpha-gal, and these antibodies (anti- Gal) cause an allergic reaction. Due to its potential immunogenicity, it is important therefore to screen biopharmaceuticals for alpha-gal. Some drug developers are also investigating the use of anti-Gal for tumour therapies.

Form: Dried by centrifugal evaporation from an aqueous solution.
Number of Samples: Typically, 100 fmol to 10 pmol of the Alpha Gal 2-AB glycan can be detected, dependent on the sensitivity of the fluorometer, HPLC or mass spectrometer.
Detection Fluorescence detection: 320 nm excitation wavelength, 420 nm emission wavelength.