Anti-Human CD8a FITC
货 号：11-0086-41
产品规格：25tests
原 产 地：USA
参考价格：948 （参考价格，以实际价格为准）
优惠价格：
Anti-Human CD8a FITC
11-0086-41
25tests
USA
The OKT8 monoclonal antibody reacts with the human CD8a molecule, anapproximately 32-34 kDa
cell surface receptor expressed either as a heterodimer with the CD8 βchain (CD8 αβ) or
as a homodimer (CD8 αα). A majority of thymocytes and a subpopulationof mature T cells
and NK cells express CD8a. CD8 binds to MHC class I and through itsassociation with protein
tyrosine kinase p56lck plays a role in T-cell development andactivation of mature T cells.
Preliminary testing indicates that OKT8 and two other mouse anti-human CD8
antibodies (clone RPA-T8, Cat. No.14-0088 and clone HIT8a, Cat.No.14-0089) do not
compete with each other for binding to human peripheral bloodleukocytes by flow cytometric
analysis, suggesting that they do not bind to similar epitopes or blockeach other by steric hindrance.
产品详细信息
Anti-Human CD8a FITC
11-0086-41
25tests
USA
The OKT8 monoclonal antibody reacts with the human CD8a molecule, anapproximately 32-34 kDa
cell surface receptor expressed either as a heterodimer with the CD8 βchain (CD8 αβ) or
as a homodimer (CD8 αα). A majority of thymocytes and a subpopulationof mature T cells
and NK cells express CD8a. CD8 binds to MHC class I and through itsassociation with protein
tyrosine kinase p56lck plays a role in T-cell development andactivation of mature T cells.
Preliminary testing indicates that OKT8 and two other mouse anti-human CD8
antibodies (clone RPA-T8, Cat. No.14-0088 and clone HIT8a, Cat.No.14-0089) do not
compete with each other for binding to human peripheral bloodleukocytes by flow cytometric
analysis, suggesting that they do not bind to similar epitopes or blockeach other by steric hindrance.