D-myo-Inositol-4-phosphate (ammonium salt)

D-myo-Inositol-4-phosphate (ammonium salt)

细胞信号传输中的可溶性第二信使
98%

有货

D-myo-Inositol-4-phosphate (ammonium salt)

CAS编号 142760-33-6 | 品牌:Jinpan
D-myo-Inositol-4-phosphate (ammonium salt)

MSDS

质检证书(CoA)

相似产品

  • 分子式 C6H11O9P·NH4
  • 分子量277.2
  • PubChem编号 16219504

货号 (SKU) 包装规格 是否现货 价格 数量
D350852-100μg 100μg 现货 D-myo-Inositol-4-phosphate (ammonium salt)  
D350852-500μg 500μg 期货 D-myo-Inositol-4-phosphate (ammonium salt)  

基本信息

产品名称 D-myo-Inositol-4-phosphate (ammonium salt)
英文名称 D-myo-Inositol-4-phosphate (ammonium salt)
英文别名 Ins(4)P1 (ammonium salt);ammonium (1S,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl hydrogenphosphate
规格或纯度 98%
运输条件 超低温冰袋运输

一般描述

D-myo-Inositol-4-phosphate (Ins(4)P1)是磷酸肌醇(InsP)分子家族的成员,在细胞信号的传输中作为小的,可溶的第二信使发挥着关键作用。1,2Ins (1,4,5)P3是由磷脂酶C(PLC)介导的磷脂酰肌醇-4,5-二磷酸水解产生的第二种信使,也是对InsP研究最多的信使。Ins(1,4,5)P3与其在内质网上的受体的结合导致钙通道的开放和细胞内钙的增加。Ins(4)P1可以通过肌醇多磷酸1-磷酸酶对Ins(1,4)P2进行磷酸化来形成,也可以通过肌醇单磷酸酶被磷酸化为肌醇来形成。


D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that plays a critical roles as small, soluble second messengers in the transmission of cellular signals.1,2 Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate, and is the most studied of the InsP. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in the opening of calcium channels and an increase in intracellular calcium. Ins(4)P1 can be formed by dephosphorylation of Ins(1,4)P2 by inositol polyphosphate 1-phosphatase or dephosphorylated to inositol by inositol monophosphatase.

相关属性

CAS编号 142760-33-6
储存温度 -20°C储存
分子量 277.2
分子式 C6H11O9P·NH4
品牌 Jinpan
Smiles C1(C(C(C(C(C1O)O)OP(=O)([O-])[O-])O)O)O.[NH4+].[NH4+]
PubChem CID 16219504