N，N-二去甲基-O-去甲基-（外消旋-文拉法辛）葡萄糖醛酸

N，N-去甲基-O-去甲基-（外消旋-文拉法辛）葡糖苷酸是文拉法辛的代谢产物。文拉法辛是苯乙胺的衍生物，据报道可通过阻止神经胺如5-羟色胺（5-羟色胺； 5-HT）和去甲肾上腺素（去甲肾上腺素）的突触前再摄取来促进中枢神经系统内的神经传递。还报道了文拉法辛 是多巴胺再摄取的弱抑制剂。|体外研究表明，文拉法辛 对毒蕈碱，组胺能或α-1肾上腺素受体没有明显的活性。据报道，文拉法辛的代谢是通过细胞色素P450（CYP）酶CYP2D6发生的，产生O-去甲基文拉法辛。CYP3A4产生较少的代谢产物N-去甲基文拉法辛

N,N-Didesmethyl-O-desmethyl-(rac-Venlafaxine) Glucuronide is a metabolite of Venlafaxine (sc-201102). Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake.|In vitro|studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.
N,N-Didesmethyl-O-desmethyl-(rac-Venlafaxine) Glucuronideis a metabolite of Venlafaxine

可替宁N-(4-脱氧-4,5-二去氢)-β-D-葡糖苷酸

可替宁N-(4-脱氧-4,5-二去氢)-β-D-葡糖苷酸 是人体内尼古丁的主要代谢产物，是已知的致癌物。

Cotinine N-(4-Deoxy-4,5-didehydro)-β-D-glucuronide is a major metabolite of Nicotine in humans which is a known carcinogen.